Gene
lin7a
- ID
- ZDB-GENE-040426-1665
- Name
- lin-7 homolog A (C. elegans)
- Symbol
- lin7a Nomenclature History
- Previous Names
-
- zgc:73090
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have L27 domain binding activity. Predicted to be involved in maintenance of epithelial cell apical/basal polarity; neurotransmitter secretion; and protein localization to basolateral plasma membrane. Predicted to localize to MPP7-DLG1-LIN7 complex; basolateral plasma membrane; and synapse. Is expressed in myotome and nervous system. Orthologous to human LIN7A (lin-7 homolog A, crumbs cell polarity complex component).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73090 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001478 | PDZ domain |
| Domain | IPR004172 | L27 domain |
| Domain | IPR014775 | L27 domain, C-terminal |
| Family | IPR017365 | Protein lin-7 |
| Family | IPR051109 | Membrane-associated multiprotein complex regulator |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Homologous_superfamily | IPR036892 | L27 domain superfamily |
Domain Details Per Protein
| Protein | Length | L27 domain | L27 domain, C-terminal | L27 domain superfamily | Membrane-associated multiprotein complex regulator | PDZ domain | PDZ superfamily | Protein lin-7 |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BC73
|
225 | |||||||
|
UniProtKB:Q6PC63
|
218 |
Interactions and Pathways
No data available
Plasmids
No data available