Gene
rcvrn3
- ID
- ZDB-GENE-040426-1661
- Name
- recoverin 3
- Symbol
- rcvrn3 Nomenclature History
- Previous Names
-
- rcv2b (1)
- zgc:73075
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity. Acts upstream of or within cone photoresponse recovery. Is expressed in epiphysis and retina. Orthologous to human RCVRN (recoverin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zang et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | Recoverin family |
|---|---|---|---|---|---|
|
UniProtKB:Q1LUD3
|
191 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rcvrn3-201
(1)
|
Ensembl | 3,507 nt | ||
| mRNA |
rcvrn3-202
(1)
|
Ensembl | 633 nt | ||
| mRNA |
rcvrn3-203
(1)
|
Ensembl | 965 nt |
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Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-rcvrn3 | polyclonal | Rabbit |
|
2 |
1 - 1 of 1
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-232M10 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:73075 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_200825 (1) | 3571 nt | ||
| Genomic | GenBank:BX950195 (2) | 149624 nt | ||
| Polypeptide | UniProtKB:Q1LUD3 (1) | 191 aa |
- Ogawa, Y., Corbo, J.C. (2021) Partitioning of gene expression among zebrafish photoreceptor subtypes. Scientific Reports. 11:17340
- Zang, J., Gesemann, M., Keim, J., Samardzija, M., Grimm, C., Neuhauss, S.C. (2021) Circadian regulation of vertebrate cone photoreceptor function. eLIFE. 10:
- Ahrens, N., Elbers, D., Greb, H., Janssen-Bienhold, U., Koch, K.W. (2020) Interaction of G protein-coupled receptor kinases and recoverin isoforms is determined by localization in zebrafish photoreceptors. Biochimica et biophysica acta. Molecular cell research. 1868(4):118946
- Henson, H.E., Taylor, M.R. (2020) A sart1 Zebrafish Mutant Results in Developmental Defects in the Central Nervous System. Cells. 9(11):
- Elbers, D., Scholten, A., Koch, K.W. (2018) Zebrafish Recoverin Isoforms Display Differences in Calcium Switch Mechanisms. Frontiers in molecular neuroscience. 11:355
- Schredelseker, T., Driever, W. (2018) Bsx controls pineal complex development. Development (Cambridge, England). 145(13):
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Zang, J., Keim, J., Kastenhuber, E., Gesemann, M., Neuhauss, S.C. (2015) Recoverin depletion accelerates cone photoresponse recovery. Open Biology. 5(8)
- Konzer, A., Ruhs, A., Braun, H., Jungblut, B., Braun, T., and Krueger, M. (2013) Stable Isotope Labeling in Zebrafish Allows in Vivo Monitoring of Cardiac Morphogenesis. Molecular & cellular proteomics : MCP. 12(6):1502-12
- Webb, K.J., Norton, W.H.J., Trumbach, D., Meijer, A.H., Ninkovic, J., Topp, S., Heck, D., Marr, C., Wurst, W., Theis, F.J., Spaink, H.P., and Bally-Cuif, L. (2009) Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine. Genome biology. 10(7):R81
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