Gene

foxi3b

ID

ZDB-GENE-031126-4

Name

forkhead box I3b

Symbol

foxi3b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in epidermal cell fate specification. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 4. Is expressed in ectoderm; integument; ionocyte; trunk; and yolk. Orthologous to several human genes including FOXI1 (forkhead box I1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 8 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With foxi3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Craniofacial microsomia 2	620444

Associated With foxi3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018122	Fork head domain conserved site1
Conserved_site	IPR030456	Fork head domain conserved site 2
Domain	IPR001766	Fork head domain
Family	IPR050211	Forkhead box domain-containing protein
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily