Gene
gemin5
- ID
- ZDB-GENE-031112-9
- Name
- gem (nuclear organelle) associated protein 5
- Symbol
- gemin5 Nomenclature History
- Previous Names
-
- cb926 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to be a structural constituent of ribosome. Involved in T cell differentiation. Predicted to localize to ribosome. Is expressed in several structures, including alar plate midbrain region; cerebellum; liver; midbrain; and segmental plate. Orthologous to human GEMIN5 (gem nuclear organelle associated protein 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb926 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
neurodevelopmental disorder with cerebellar atrophy and motor dysfunction | Alliance | Neurodevelopmental disorder with cerebellar atrophy and motor dysfunction | 619333 |
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
cerebellar ataxia | gemin5it342/it342 | standard conditions | Saida et al., 2021 |
cerebellar ataxia | gemin5it343/it343 | standard conditions | Saida et al., 2021 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR019775 | WD40 repeat, conserved site |
Domain | IPR024977 | Anaphase-promoting complex subunit 4-like, WD40 domain |
Family | IPR052640 | WD repeat domain-containing protein Gemin-5 |
Homologous_superfamily | IPR011047 | Quinoprotein alcohol dehydrogenase-like superfamily |
Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
Protein | Length | Anaphase-promoting complex subunit 4-like, WD40 domain | Quinoprotein alcohol dehydrogenase-like superfamily | WD40 repeat | WD40 repeat, conserved site | WD40/YVTN repeat-like-containing domain superfamily | WD repeat domain-containing protein Gemin-5 |
---|---|---|---|---|---|---|---|
UniProtKB:E9QH84
|
1440 | ||||||
UniProtKB:A0A8M3AX38
|
1439 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
gemin5-201
(1)
|
Havana | 4516 nt | |
mRNA |
gemin5-202
(1)
|
Ensembl | 615 nt |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-gemin5 | monoclonal | IgG2a | Mouse |
|
2 |
Plasmids
No data available