Gene
trpv1
- ID
- ZDB-GENE-030912-8
- Name
- transient receptor potential cation channel, subfamily V, member 1
- Symbol
- trpv1 Nomenclature History
- Previous Names
-
- TRPV1/2 (1)
- si:dkey-9e15.2
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have calcium channel activity. Involved in response to heat and thermosensory behavior. Predicted to localize to integral component of plasma membrane. Is expressed in several structures, including epithelium; heart; keratinocyte; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in colorectal cancer; congenital stationary night blindness; keratosis (multiple); migraine (multiple); and schizophrenia. Orthologous to several human genes including TRPV1 (transient receptor potential cation channel subfamily V member 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 13 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chen et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR005821 | Ion transport domain |
Family | IPR008347 | Transient receptor potential cation channel subfamily V member 1-4 |
Family | IPR024862 | Transient receptor potential cation channel subfamily V |
Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Ion transport domain | Transient receptor potential cation channel subfamily V | Transient receptor potential cation channel subfamily V member 1-4 |
---|---|---|---|---|---|---|
UniProtKB:B6RTA2
|
819 | |||||
UniProtKB:B0S711
|
813 |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-trpv1 | polyclonal | IgG | Rabbit |
|
Thermo Fisher Scientific (Lab Vision)
|
2 |
Plasmids
No data available