Gene
glo1
- ID
- ZDB-GENE-030722-9
- Name
- glyoxalase 1
- Symbol
- glo1 Nomenclature History
- Previous Names
-
- cb554 (1)
- wu:fb82g09
- zgc:66035
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have lactoylglutathione lyase activity and metal ion binding activity. Human ortholog(s) of this gene implicated in autistic disorder; diabetic retinopathy; end stage renal failure; type 2 diabetes mellitus; and vascular disease. Is expressed in several structures, including alar plate midbrain region; digestive system; eye; midbrain; and segmental plate. Orthologous to human GLO1 (glyoxalase I).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb554 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018146 | Glyoxalase I, conserved site |
| Domain | IPR004360 | Glyoxalase/fosfomycin resistance/dioxygenase domain |
| Domain | IPR037523 | Vicinal oxygen chelate (VOC) domain |
| Family | IPR004361 | Glyoxalase I |
| Homologous_superfamily | IPR029068 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
Domain Details Per Protein
| Protein | Length | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | Glyoxalase/fosfomycin resistance/dioxygenase domain | Glyoxalase I | Glyoxalase I, conserved site | Vicinal oxygen chelate (VOC) domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6P696
|
180 |
Interactions and Pathways
No data available
Plasmids
No data available