Gene

mpx

ID
ZDB-GENE-030131-9460
Name
myeloid-specific peroxidase
Symbol
mpx Nomenclature History
Previous Names
  • drf
  • fj80f04
  • mpo (1)
  • myeloperoxidase (1)
  • unm t30963
  • unm_sm681
  • unm_t30963
  • wu:fj80f04
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Exhibits peroxidase activity. Involved in inflammatory response; regulation of hydrogen peroxide metabolic process; and response to bacterium. Localizes to cytoplasm. Is expressed in several structures, including hematopoietic cell; hematopoietic system; mesoderm; pleuroperitoneal region; and post-vent region.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
350 figures from 238 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mpx Human Ortholog
No data available
Associated With mpx Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001073 C1q domain
Family IPR019791 Haem peroxidase, animal-type
Homologous_superfamily IPR008983 Tumour necrosis factor-like domain superfamily
Homologous_superfamily IPR010255 Haem peroxidase superfamily
Homologous_superfamily IPR037120 Haem peroxidase domain superfamily, animal type
Domain Details Per Protein
Protein Length C1q domain Haem peroxidase, animal-type Haem peroxidase domain superfamily, animal type Haem peroxidase superfamily Tumour necrosis factor-like domain superfamily
UniProtKB:A0A8M9Q5S9 892
UniProtKB:A0A8M1P4H4 893
UniProtKB:Q90XS6 762
UniProtKB:F1Q944 762
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mpx-201 (1) Ensembl 3,146 nt
mRNA mpx-202 (1) Ensembl 3,199 nt
ncRNA mpx-003 (1) Ensembl 1,481 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab5-mpx polyclonal IgG Rabbit
  • IHC
GeneTex
22
Ab1-mpx polyclonal Rabbit
  • IHC
8
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations