Gene

sh3rf1

ID
ZDB-GENE-030131-6288
Name
SH3 domain containing ring finger 1
Symbol
sh3rf1 Nomenclature History
Previous Names
  • fi42f11
  • si:ch211-114c9.2
  • si:dkey-15j16.4
  • wu:fi42f11
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have MAP-kinase scaffold activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including positive regulation of JNK cascade; protein autoubiquitination; and regulation of alpha-beta T cell activation. Predicted to localize to lamellipodium. Orthologous to several human genes including SH3RF1 (SH3 domain containing ring finger 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sh3rf1 Human Ortholog
No data available
Associated With sh3rf1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017907 Zinc finger, RING-type, conserved site
Domain IPR001452 SH3 domain
Domain IPR001841 Zinc finger, RING-type
Domain IPR027370 Zinc finger, RING-type, eukaryotic
Domain IPR035795 E3 ubiquitin-protein ligase SH3RF1, second SH3 domain
Domain IPR035816 SH3RF1/SH3RF3, fourth SH3 domain
Family IPR050384 Endophilin/SH3RF
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Length E3 ubiquitin-protein ligase SH3RF1, second SH3 domain Endophilin/SH3RF SH3 domain SH3-like domain superfamily SH3RF1/SH3RF3, fourth SH3 domain Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, RING-type, conserved site Zinc finger, RING-type, eukaryotic
UniProtKB:B3DIT8 880
UniProtKB:A5D8S5 867
UniProtKB:A0A8M1N9B8 857
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sh3rf1-201 (1) Ensembl 4,714 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations