Gene

tnfrsf21

ID
ZDB-GENE-030131-5971
Name
tumor necrosis factor receptor superfamily, member 21
Symbol
tnfrsf21 Nomenclature History
Previous Names
  • DR6 (2)
  • im:6795346
  • wu:fa55e01 (1)
  • wu:fb02e11 (1)
  • wu:fc29a09 (1)
  • wu:fi27h08 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Involved in establishment of endothelial blood-brain barrier and sprouting angiogenesis. Predicted to localize to integral component of plasma membrane. Is expressed in floor plate; forerunner cell group; and pronephric duct. Orthologous to human TNFRSF21 (TNF receptor superfamily member 21).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Tam et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tnfrsf21 Human Ortholog
No data available
Associated With tnfrsf21 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000488 Death domain
Domain IPR001368 TNFR/NGFR cysteine-rich region
Domain IPR034034 Tumor necrosis factor receptor 21, N-terminal
Domain IPR034037 Tumor necrosis factor receptor 21, death domain
Family IPR022330 Tumour necrosis factor receptor 21
Homologous_superfamily IPR011029 Death-like domain superfamily
Domain Details Per Protein
Protein Length Death domain Death-like domain superfamily TNFR/NGFR cysteine-rich region Tumor necrosis factor receptor 21, death domain Tumor necrosis factor receptor 21, N-terminal Tumour necrosis factor receptor 21
UniProtKB:A5D8S6 637
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tnfrsf21-201 (1) Ensembl 4,854 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-tnfrsf21
  • IHC
1
Ab1-tnfrsf21
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations