Gene

bnc2

ID

ZDB-GENE-030131-5784

Name

basonuclin zinc finger protein 2

Symbol

bnc2 Nomenclature History

Previous Names

bnp
coral
crl
fi18b05
poppy (1)
si:dkey-114f6.1
wu:fi18b05

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to enable metal ion binding activity. Acts upstream of or within developmental pigmentation and pronephric nephron tubule development. Located in nucleus. Is expressed in several structures, including centrum; gut; hypodermal cell; nervous system; and pleuroperitoneal region. Used to study urinary tract obstruction. Orthologous to human BNC2 (basonuclin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 12 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bnc2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Lower urinary tract obstruction, congenital	618612

Associated With bnc2 Via Experimental Models

Human Disease	Fish	Conditions	Citations
urinary tract obstruction	AB/TL + MO1-bnc2	standard conditions	Kolvenbach et al., 2019
urinary tract obstruction	li1Tg + MO1-bnc2	standard conditions	Kolvenbach et al., 2019
urinary tract obstruction	nkhgj4aEt + MO1-bnc2	standard conditions	Kolvenbach et al., 2019

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR013087	Zinc finger C2H2-type
Family	IPR040436	Protein disconnected-like

Domain Details Per Protein

Protein	Length	Protein disconnected-like	Zinc finger C2H2-type
UniProtKB:A0A2R8QKL6 InterPro	1223
UniProtKB:A0A0R4IKC9 InterPro	1268
UniProtKB:C7DZJ6 InterPro	1171
UniProtKB:F1R425 InterPro	978

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	bnc2-201 (1) Ensembl	Ensembl	4,758 nt	Select Tool ZFIN BLAST
mRNA	bnc2-202 (1) Ensembl	Ensembl	4,621 nt	Select Tool ZFIN BLAST
mRNA	bnc2-203 (1) Ensembl	Ensembl	5,177 nt	Select Tool ZFIN BLAST
mRNA	bnc2-204 (1) Ensembl	Ensembl	7,463 nt	Select Tool ZFIN BLAST
mRNA	bnc2-205 (1) Ensembl	Ensembl	8,162 nt	Select Tool ZFIN BLAST
mRNA	bnc2-206 (1) Ensembl	Ensembl	7,763 nt	Select Tool ZFIN BLAST
mRNA	bnc2-207 (1) Ensembl	Ensembl	8,435 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab2-bnc2	polyclonal	bnc2		Rabbit	IHC	Sigma-Aldrich	1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations