Gene

cdk9

ID
ZDB-GENE-030131-321
Name
cyclin-dependent kinase 9 (CDC2-related kinase)
Symbol
cdk9 Nomenclature History
Previous Names
  • wu:fb22e09
  • wu:fc06c02
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have several functions, including cyclin binding activity; protein serine/threonine kinase activity; and transcription regulatory region DNA binding activity. Involved in cardiac muscle tissue regeneration; inflammatory response to wounding; and regulation of cardiac muscle cell proliferation. Predicted to localize to cyclin/CDK positive transcription elongation factor complex and nuclear chromatin. Orthologous to human CDK9 (cyclin dependent kinase 9).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
16 figures from 7 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdk9 Human Ortholog
No data available
Associated With cdk9 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Family IPR050108 Cyclin-dependent kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Cyclin-dependent kinase Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:Q7SXE8 374
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cdk9-201 (1) Ensembl 1,782 nt
mRNA cdk9-202 (1) Ensembl 1,698 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab3-cdk9 monoclonal IgG Rabbit
  • IHC
  • WB
Cell Signaling Technology, Inc.
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations