Gene
bptf
- ID
- ZDB-GENE-030131-3200
- Name
- bromodomain PHD finger transcription factor
- Symbol
- bptf Nomenclature History
- Previous Names
-
- fc30e02
- fc32a05
- wu:fb71f11
- wu:fc30e02
- wu:fc32a05
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cranial skeletal system development; neural plate anterior/posterior regionalization; and nucleosome positioning. Predicted to localize to NURF complex. Is expressed in head. Orthologous to human BPTF (bromodomain PHD finger transcription factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| neurodevelopmental disorder with dysmorphic facies and distal limb anomalies | Alliance | Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies | 617755 |
| {Kaposi sarcoma, susceptibility to} | 148000 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018359 | Bromodomain, conserved site |
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR001487 | Bromodomain |
| Domain | IPR001510 | Zinc finger, PARP-type |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR018501 | DDT domain |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR028941 | WHIM2 domain |
| Family | IPR038028 | Nucleosome-remodeling factor subunit BPTF |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036427 | Bromodomain-like superfamily |
Domain Details Per Protein
| Protein | Length | Bromodomain | Bromodomain, conserved site | Bromodomain-like superfamily | DDT domain | Nucleosome-remodeling factor subunit BPTF | WHIM2 domain | Zinc finger, FYVE/PHD-type | Zinc finger, PARP-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AQI5
|
2900 | ||||||||||||
|
UniProtKB:E7F366
|
2899 | ||||||||||||
|
UniProtKB:A0A8M6Z5Q1
|
2843 | ||||||||||||
|
UniProtKB:A0A8M3AXZ5
|
2873 | ||||||||||||
|
UniProtKB:A0A8M6YWR8
|
2816 | ||||||||||||
|
UniProtKB:A0A8M3AQV1
|
2899 | ||||||||||||
|
UniProtKB:A0A8M3B0X4
|
2891 | ||||||||||||
|
UniProtKB:A0A8M2BJ03
|
2885 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance