Gene

nav3

ID

ZDB-GENE-021205-1

Name

neuron navigator 3

Symbol

nav3 Nomenclature History

Previous Names

cb419 (1)
wu:fa05f06

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Exhibits actin binding activity. Involved in liver morphogenesis and pancreas development. Localizes to Golgi apparatus; filopodium; and lamellipodium. Is expressed in several structures, including cardiovascular system; digestive system; liver primordium; nervous system; and periderm. Orthologous to human NAV3 (neuron navigator 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb419 (27 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Klein et al., 2011
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nav3 Human Ortholog

No data available

Associated With nav3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001715	Calponin homology domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR003959	ATPase, AAA-type, core
Family	IPR039041	Nav/unc-53 family
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036872	CH domain superfamily

Domain Details Per Protein

Protein	Length	AAA+ ATPase domain	ATPase, AAA-type, core	Calponin homology domain	CH domain superfamily	Nav/unc-53 family	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M6YX31 InterPro	2411
UniProtKB:Q5TZ18 InterPro	2269
UniProtKB:A0A8M9Q0Q8 InterPro	2208
UniProtKB:A0A8M9PHG5 InterPro	2412
UniProtKB:A0A8M9PHH5 InterPro	2350
UniProtKB:A0A8M9Q620 InterPro	1464
UniProtKB:A0A8M9QBG6 InterPro	2383
UniProtKB:A0A8M9QBH1 InterPro	1924
UniProtKB:A0A8M9PUQ7 InterPro	2221
UniProtKB:A0A8M9PUQ1 InterPro	2395
UniProtKB:A0A8M3ARI4 InterPro	2373
UniProtKB:A0A8M9QBF3 InterPro	2418
UniProtKB:A0A8M9Q610 InterPro	2417
UniProtKB:A0A8M9QBF8 InterPro	2409
UniProtKB:A0A8M3B919 InterPro	2368
UniProtKB:A0A8M9PUP3 InterPro	2411
UniProtKB:A0A8M9Q0P5 InterPro	2410
UniProtKB:A0A8M9Q614 InterPro	2403
UniProtKB:A0A8M3ARS0 InterPro	2367
UniProtKB:A0A8M9Q0Q3 InterPro	2389
UniProtKB:A0A8M9PHG9 InterPro	2402

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	nav3-201 (1) Ensembl	Ensembl	7,659 nt	Select Tool
mRNA	nav3-202 (1) Ensembl	Ensembl	1,938 nt	Select Tool
mRNA	nav3-203 (1) Ensembl	Ensembl	522 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-nav3	polyclonal	nav3		Rabbit			1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations