Gene

ets1

ID
ZDB-GENE-021115-5
Name
v-ets avian erythroblastosis virus E26 oncogene homolog 1
Symbol
ets1 Nomenclature History
Previous Names
  • ets1a
  • cb516 (1)
  • id:ibd1116
  • zgc:110573
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Exhibits DNA binding activity and DNA-binding transcription factor activity. Involved in blood vessel morphogenesis. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Is expressed in several structures, including cardiovascular system; germ ring; hematopoietic system; mesoderm; and nervous system. Orthologous to human ETS1 (ETS proto-oncogene 1, transcription factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
39 figures from 15 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Chetty et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ets1 Human Ortholog
No data available
Associated With ets1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003118 Pointed domain
Domain IPR041886 Protein C-ets-1, pointed domain
Domain IPR045688 Ets1, N-terminal flanking region of Ets domain
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Domain Details Per Protein
Protein Length Ets1, N-terminal flanking region of Ets domain Pointed domain Protein C-ets-1, pointed domain Sterile alpha motif/pointed domain superfamily
UniProtKB:Q568B4 334
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ets1-201 (1) Ensembl 798 nt
mRNA ets1-202 (1) Ensembl 795 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations