Gene
aurkb
- ID
- ZDB-GENE-020419-40
- Name
- aurora kinase B
- Symbol
- aurkb Nomenclature History
- Previous Names
-
- aurB (1)
- cei
- cellular island
- CHUNP6896
- fa09g06
- fd02h12
- stka
- wu:fa09g06
- wu:fd02h12
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable histone serine kinase activity. Acts upstream of or within chromosome segregation; cytoskeleton-dependent cytokinesis; and microtubule cytoskeleton organization. Predicted to be located in midbody and nucleus. Predicted to be part of chromosome passenger complex. Predicted to be active in spindle microtubule; spindle midzone; and spindle pole centrosome. Is expressed in several structures, including blastomere; midbrain hindbrain boundary; nervous system; and proliferative region. Human ortholog(s) of this gene implicated in spermatogenic failure 5. Orthologous to several human genes including AURKB (aurora kinase B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85918 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aurora kinase-like | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|
|
UniProtKB:F1RDC1
|
320 | |||||
|
UniProtKB:Q6NW76
|
320 |
Interactions and Pathways
No data available
Plasmids
No data available