Gene

pbx4

ID
ZDB-GENE-000201-18
Name
pre-B-cell leukemia transcription factor 4
Symbol
pbx4 Nomenclature History
Previous Names
  • pbxx
  • fb77e11
  • lazarus (1)
  • lzr
  • wu:fb77e11 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits DNA binding activity and DNA-binding transcription factor activity. Involved in several processes, including animal organ development; generation of neurons; and regulation of histone modification. Localizes to nucleus. Orthologous to human PBX4 (PBX homeobox 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
34 figures from 14 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pbx4 Human Ortholog
No data available
Associated With pbx4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR005542 PBX, PBC domain
Domain IPR008422 KN homeodomain
Family IPR050224 Three Amino acid Loop Extension (TALE) homeobox
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox, conserved site Homeodomain KN homeodomain PBX, PBC domain Three Amino acid Loop Extension (TALE) homeobox
UniProtKB:Q9PW77 343
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pbx4-201 (1) Ensembl 4,379 nt
mRNA pbx4-202 (1) Ensembl 827 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-pbx polyclonal Rabbit
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations