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Fig. 1

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ZDB-FIG-240624-69

Publication

Fagundes et al., 2024 - The generation gap in endocrine disruption: Can the integrated fish endocrine disruptor test (iFEDT) bridge the gap by assessing intergenerational effects of thyroid hormone system disruption?

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Fig. 1

Exposure design of iFEDT experiment and cross design experiment: Zebrafish (Danio rerio) parents and offspring were exposed to PTU (iFEDT, results published in Pannetier et al. 2023a and Goelz et al. 2023). For the present study, eggs from the non-exposed parental generation (0 mg PTU/L) were exposed to either 0 or 78 mg PTU /L. Likewise, eggs from the parental generation exposed to 78 mg PTU/L were exposed to either 0 or 78 mg PTU /L. Between 4 and 18 days of exposure of the parental generation, eggs were collected and directly exposed for 4.5 d for evaluation of photomotor response and gene expression, or for 5 d for measurement of area of swim bladder.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Aquat. Toxicol.