FIGURE

Figure 6

ID

ZDB-FIG-240610-6

Publication

Pawlowska et al., 2024 - Double-modified, thio and methylene ATP analogue facilitates wound healing in vitro and in vivo

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Figure 6

Impact of α-thio-β,γ-methylene-ATP on the epithelial–mesenchymal transition- related changes in the model MDA-MB-231 cells. (A) Transwell migration rate of cells through 8 μm pore sizes. Data represent the means ± SEM from at least 3 independent experiments, (B) Crossing the collagen barrier in the presence of tested compounds. (C) The impact of tested analogues on in vivo cells migration in zebrafish xenograft model (D) QPCR analysis of EMT markers after treatment with 4a and 4b. Data represent the means ± SEM from at least 3 independent experiments ***p < 0.0005, **p < 0.001, *p < 0.05 compared to the control.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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