FIGURE

Fig. 5

ID

ZDB-FIG-240328-26

Publication

Merola et al., 2023 - Embryonic and larval exposure to propylparaben induces developmental and long-term neurotoxicity in zebrafish model

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Fig. 5

(A) Human phenotypes significantly enriched in juveniles zebrafish brains by PrP 10 μg/L and PrP 1000 μg/L treatments. The size of the points is proportional to the number of featured proteins whereas significance is indicated by the red (more significant) to blue (less significant) gradient. (B, C) Gene-disease association networks in juveniles zebrafish brains induced by PrP 10 μg/L (C) and PrP 1000 μg/L (B) treatments. Disease colors indicate the category: pink for “Mental disorders”, green for “Nervous System Diseases”, and orange for “Behavior and Behavior Mechanisms”. (C) Gene Expression levels of the selected genes shank3a, gad1b, ilvbl, dlg1 lin 60 dpf specimens. Shank3a, gad1b, ilvbl, dlg1l were assessed in 9 brains for each condition of 60 dpf zebrafish. Data are presented as means ± SEM. * indicates significant differences in transcript levels vs control (DMSO 0.1 %). *p < 0.05; **p < 0.005.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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