FIGURE

Figure 3

ID

ZDB-FIG-240307-55

Publication

Şerifoğlu et al., 2024 - Lack of telomerase reduces cancer incidence and increases lifespan of zebrafish tp53^M214K mutants

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Figure 3

tp53 does not rescue chronic inflammation of the telomerase-deficient zebrafish. (A) RT-qPCR analysis of isg15 in head kidney (n_WT = 6, n_tert−/− = 6, n_p53−/− = 6, n_{tert−/− tp53mut} = 6). (B) RT-qPCR analysis of ifn-i in head kidney (n_WT = 6, n_tert−/− = 6, n_p53−/− = 6, n_{tert−/− tp53mut} = 6). (C) RT-qPCR analysis of mmp15a in head kidney (n_WT = 6, n_tert−/− = 6, n_p53−/− = 6, n_{tert−/− tp53mut} = 6). Statistical tests were performed using a one-way ANOVA, **p < 0.01, *p < 0.05.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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