FIGURE

Fig. 2

ID

ZDB-FIG-231215-97

Publication

Farmer et al., 2021 - Comprehensive series of Irx cluster mutants reveals diverse roles in facial cartilage development

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Requirement for IrxB genes in pectoral fin development. (A) Alcian Blue (cartilage) and Alizarin Red (bone) staining of pectoral fins shows reductions of the scapulocoracoid cartilage in IrxBa−/−; IrxBb+/− mutants. (B) Summary of genotypes for the reduced pectoral girdle phenotype from a quintuple heterozygous in-cross. P-values report chi-square tests for deviation from the expected 1:2:1 wild type:heterozygous:homozygous Mendelian ratio. (C) Model highlighting the conserved roles of IrxB genes in development of proximal structures of the mouse forelimb and zebrafish pectoral fin. Green shading indicates regions for which development is dependent on IrxB/IrxBa. Cl, cleithrum; ED, endoskeletal disc cartilage; Hu, humerus; POP, postcoracoid process; Ra, radius; S, scapula; Sc, scapulocoracoid cartilage; Ul, ulna. Scale bar: 100 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	irx3b^el837/el837; irx5b^el722/el722 irx3a^el835/el835; irx3b^el837/el837; irx5a^el576/el576; irx5b^el722/el722; irx6a^el836/el836
Observed In:	pectoral girdle scapulocoracoid
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development