FIGURE

Fig. 5

ID

ZDB-FIG-231122-33

Publication

LeBleu et al., 2023 - Identification of unique α4 chain structure and conserved anti-angiogenic activity of α3NC1 type IV collagen in zebrafish

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Fig. 5

Tissue distribution of the six collagen IV α chains in zebrafish development. (A) In situ hybridization for zebrafish α6 chains at 36 hpf in the brain (b), otic vesicle (o), gills (g), developing cardiac tissue (c), and the pronephric duct (pn) of the future kidney. (B) RT-PCR products in adult zebrafish for the six α chains are shown above the positive control β-actin. All six α chains are detectable in brain, gills, kidney, skeletal muscle, swim bladder, and testes. Gut/bowel and skin express the α1, α2, α5, and α6 chains only. Liver and heart both display expression of all α chains except the α3 chain.

Expression Data

Genes:	col4a1 col4a2 col4a3 col4a4 col4a5 col4a6
Fish:	AB/TL
Anatomical Terms:	brain gill gonad primordium gut heart tube integument liver muscle otic vesicle peripheral olfactory organ pronephros swim bladder bud
Stage:	Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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