FIGURE

Fig 4

ID

ZDB-FIG-230823-9

Publication

Islam et al., 2023 - The RNA-binding protein Adad1 is necessary for germ cell maintenance and meiosis in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig 4

Histology of wild-type and adad1^Y67X mutant gonads at 45, 60, and 90 dpf.

A-B: At 45 dpf, germ cells are present in both the wild-type (N = 8) (A) and mutant (N = 8) (B) testes. C-D: At 60 dpf, spermatogonia (Sg, red outline) and spermatocytes (Sc, blue outline) are present in both wild-type (N = 10) (C) and mutant (D), but the mutant lacks mature sperm (N = 10) (Sp, yellow outline). E-F: At 90 dpf, the wild-type testis is larger with abundant sperm (N = 6) (E) whereas the mutant testis is small and devoid of germ cells (N = 6) (F). Dotted red lines outline the gonads in A, B and F. Scale bar: 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	adad1^{sa14397/sa14397}
Observed In:	germ line cell male germ-line stem cell population maintenance sperm spermatocyte spermatogenesis spermatogonium testis
Stage Range:	Days 45-89 to Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.