FIGURE

Fig. 5

ID

ZDB-FIG-230517-11

Publication

Kayser et al., 2022 - Clock genes rescue nphp mutations in zebrafish

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Fig. 5

Resilience of nphp4 mutant zebrafish lines against MO-mediated nphp4 depletion. Wild-type siblings (+/+) or homozygote nphp4 mutants (m/m) zebrafish embryos were treated with SBM or TBM (0.1 or 0.2 mm). Glomerular cyst and cloaca malformation were expressed as fold change in relationship to control MO-injected zebrafish embryos (0.2 mm). While wild-type siblings remained sensitive to either SBM or TBM and primarily developed glomerular cysts, mutant zebrafish displayed a blunted response, suggesting resistance to MO-mediated nphp4 depletion. The numbers displayed below the graph depict the respective group size.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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