FIGURE
Figure 6
- ID
- ZDB-FIG-230515-94
- Publication
- Arroyo et al., 2023 - NAMPT and PARylation Are Involved in the Pathogenesis of Atopic Dermatitis
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Figure 6
NAD+ and PAR metabolism is involved in AD pathogenesis. PARP1 hyperactivation in keratinocytes fueled by NAMPT-derived NAD+ exacerbates the inflammation and hyperplasia of AD. Consequently, pharmacological inhibition of NAMPT and PARP1 decreases disease-associated inflammation and proliferation, restoring skin homeostasis. Smartservier resources have been used to generate this figure. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Full text @ Int. J. Mol. Sci.