FIGURE
Figure 2
- ID
- ZDB-FIG-230401-40
- Publication
- Dong et al., 2023 - Augmentation of Pectoral Fin Teratogenicity by Thalidomide in Human Cytochrome P450 3A-Expressing Zebrafish
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Figure 2
Effects of thalidomide on pectoral fin development of hCYP3A7-expressing zebrafish. Embryos/larvae of wild-type (WT) zebrafish (A,B) and hCYP3A7-expressing zebrafish (3A7) (C–G) were exposed to 200 μM thalidomide (TD) or 0.02% DMSO as a vehicle from 17 hpf to 72 hpf. Arrows in (D–G) indicate pectoral fin malformation. The white arrowhead in (F) indicates bleeding in the dorsal head region. Black arrowheads show a smaller eye (F) and loss of an eye (G). Scale bar = 200 µm. A summarized graph is presented in H (n = 6, 8–26 zebrafish for each case). * p < 0.05, ** p < 0.01. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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