FIGURE

FIGURE 4

ID

ZDB-FIG-230321-16

Publication

Brown-Panton et al., 2023 - Gap junction Delta-2b (gjd2b/Cx35.1) depletion causes hyperopia and visual-motor deficiencies in the zebrafish

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FIGURE 4

Loss of Gjd2b/Cx35.1 Caused a Dysmorphic Head Feature. (A) Illustration of the zebrafish measurements taken in Image J. (B) Images of 7dpf wild-type TL and gjd2b/Cx35.1^−/− zebrafish larva. Quantification of the (C) body length, (D) head length, and (E) midbrain diameter. Gjd2b ^−/− /Cx35.1^−/− larvae were larger in both body and head length in comparison to the age-matched wild-type larvae. The (F) Head-to-Body ratio and (G) Head-to-Midbrain ratios demonstrated a reduction in the midbrain diameter in gjd2b ^−/− /Cx35.1^−/− larvae relative to their body size, suggesting a developmental alteration. The statistical significance was determined by the Mann-Whitney test, p ≤ 0.05. (C–G) Shows Estimation Plots. The sample size (N) was 19 for WT and gjd2b ^−/− /Cx35.1^−/− larvae.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol