FIGURE

Figure 4

ID

ZDB-FIG-230228-426

Publication

Sellaththurai et al., 2023 - CRISPR/Cas9-Induced Knockout of Sting Increases Susceptibility of Zebrafish to Bacterial Infection

Other Figures

All Figure Page

Back to All Figure Page

Figure 4

E. piscicida challenge in sting^(−/−) and WT zebrafish. (A) Percent mortality of sting^(−/−) and WT zebrafish post-E. piscicida infection. Two-month-old juvenile zebrafish were wounded, and E. piscicida infection was performed via bath immersion for 5 h. (B–H) Temporal transcription of tbk1, nf-κb, irf3, irf7, ifnphi1, tnfα, and il6 in juvenile sting^(−/−) and WT zebrafish upon E. piscicida infection. ef-1α expression was used as an internal control to analyze relative mRNA expression using the Livak method, and gene expression was normalized to that of the respective PBS control group. The error bars and the asterisk (* p < 0.01, ** p < 0.001) indicate the standard deviation and significantly different transcription levels compared to the respective control, respectively.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biomolecules