FIGURE

Fig. 6

ID

ZDB-FIG-221030-6

Publication

Ferre-Fernández et al., 2022 - CRISPR-Cas9-mediated functional dissection of the foxc1 genomic region in zebrafish identifies critical conserved cis-regulatory elements

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Fig. 6

foxc1a^∆CED1−3 mutant embryos display defects in the developing superficial choroidal vasculature. A–C’ Three-dimensional maximum intensity projection images of the ocular vasculature in live control (A–C) or foxc1a^∆CED1−3 homozygous (A’–C’) embryos carrying fli1a:EGFP transgene at 3-, 5- and 8-dpf. Mutant embryos show abnormal development of the dorsal and nasal radial vessels (orange arrowheads in A’–C’), enlarged and deformed superficial annular vessel (orange arrows) and a highly disorganized vasculogenesis in the ventral part of the eye with no visible ventral radial vessel at 5- and 8-dpf (orange asterisks). DRV (dorsal radial), NRV (nasal radial), SAV (superficial annular), and VRV (ventral radial) blood vessels are indicated

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Hum. Genomics