FIGURE

Fig. 1

ID

ZDB-FIG-220829-139

Publication

Yan et al., 2022 - Transcriptomic and Phenotypic Analysis of CRISPR/Cas9-Mediated gluk2 Knockout in Zebrafish

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Fig. 1

Distribution and knockout of the gluk2 gene in zebrafish. (A). The relative mRNA levels of gluk2 are determined in selected tissues of wild-type. Analysis of variance (ANOVA) and the Duncan test are applied on the data, p < 2 × 10⁻¹⁶. a−d: The same letter indicates no difference between means as determined (p < 0.05), different letters indicate a significant difference (p < 0.05). (B). gluk2 locus, with gluk2⁻^26bp mutation and a premature stop in gluk2⁻^26bp. Asterisk indicates stop codon. (C). The relative mRNA levels of gluk2 are determined in wild-type and gluk2^−/− mutant. Values plotted are means ± SEM, *** p < 0.001, compared with control. (D). The predicted three-dimensional structures of GluK2 and GluK2^−26bp.

Expression Data

Gene:	grik2
Fish:	AB grik2^sou9/sou9 (AB)
Anatomical Terms:	brain eye gill heart integument intestine kidney liver muscle oocyte spleen
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	grik2^sou9/sou9 (AB)
Observed In:	brain gill integument intestine liver
Stage:	Adult

Phenotype Detail

Acknowledgments

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