FIGURE

Figure 8

ID

ZDB-FIG-220816-63

Publication

Zeng et al., 2022 - Sexual dimorphic effects of igf1 deficiency on metabolism in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Figure 8

E2 rescue the hepatic steatosis and the AKT-mTOR signaling activity in liver. (A, B) Relative expression of gh1 gene in pitutary (A) of igf1-deficient and wild type treated in E2(100μg/L). Triglyceride composition in liver (B) of igf1-deficient and wild type treated in E2(100μg/L). An independent experiment was carried out in which the control group zebrafish was treated with 5% DMSO in fish water. (C, D) Western blot analysis of hepatic AKT-mTOR signal activity in male zebrafish. Four animals were sampled for each experiment and three biological repeats were carried out and statistical analysis was performed using a t test (p<0.001, n=3). *p < 0.05, ***P < 0.001.

Expression Data

Gene:	gh1
Antibodies:	Ab1-rps6 Ab3-akt Ab5-akt Ab5-rps6
Fish:	WT igf1^{zf3739/zf3739}
Condition:	chemical treatment by environment: 17beta-estradiol
Anatomical Terms:	hypophysis liver
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT igf1^{zf3739/zf3739}
Condition:	chemical treatment by environment: 17beta-estradiol
Observed In:	hypophysis liver liver triglyceride
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Endocrinol (Lausanne)