FIGURE

Figure 1

ID

ZDB-FIG-220801-15

Publication

Gessler et al., 2022 - Control of Directed Cell Migration after Tubular Cell Injury by Nucleotide Signaling

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Figure 1

The involvement of adenosine receptors in zebrafish pronephros repair. (A) In situ hybridization revealed upregulation of zebrafish adora1a and adora1b after a laser-induced injury. Images were obtained two hours after the injury. (B) Depletion of zebrafish adora1a or adora1b by splice- (SBM) or translation- (TBM) blocking morpholino oligonucleotides (MO) delayed the repair process. (C) In situ hybridization revealed upregulation of zebrafish adora2aa and adora2ab after a laser-induced injury. Images were obtained two hours after the injury. (D) Depletion of zebrafish adora2aa or adora2ab by SBM delayed the repair process (mean ± SEM; 2-way ANOVA).

Expression Data

Genes:	adora1a adora1b adora2aa adora2ab
Fish:	WT
Condition:	ablation: pronephros
Anatomical Term:	pronephros
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT WT + MO1-adora1a WT + MO1-adora1b WT + MO2-adora2aa WT + MO2-adora2ab
Condition:	ablation: pronephros
Knockdown Reagents:	MO1-adora1a MO1-adora1b MO2-adora2aa MO2-adora2ab
Observed In:	pronephros pronephros regeneration
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.