FIGURE

Fig. 2 - supplement 1

ID
ZDB-FIG-220617-7
Publication
Lai et al., 2022 - DNA-damage induced cell death in yap1;wwtr1 mutant epidermal basal cells
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Fig. 2 - supplement 1

Yap1 and Wwtr1 are localized to the nuclei of epidermal basal cells (EBCs), and Yap1’s Tead-binding domain is essential in EBC survival.

(Top) Schematic of the encoded protein product of the zebrafish yap1 WT and bns22 alleles. S54 is necessary for Yap1 binding to Teads. (Bottom) Maximum intensity projections of 16–18 ss WT and yap1bns22/bns22;wwtr1-/- embryos stained with TUNEL and P63. Scale bars, 100 µm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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