FIGURE

Fig 10

ID

ZDB-FIG-220331-45

Publication

Reuter et al., 2022 - Identification of an evolutionarily conserved domain in Neurod1 favouring enteroendocrine versus goblet cell fate

Other Figures

All Figure Page

Back to All Figure Page

Fig 10

Expression level of selected transcription factors in EEC from wild-type or <italic toggle='yes'>neurod1</italic><sup><italic toggle='yes'>ΔUCE</italic></sup> homozygous mutant larvae.

A: Expression level for 12 “endocrine pancreas development” genes. B: Expression level of selected genes differentially up-regulated by neurod1^ΔUCE. The expression level (given in normalized CPM) was obtained from the RNA-seq data of pax6b:GFP+ EEC isolated by FACS from wt or neurod1^ΔUCE homozygous mutant larvae at 4 dpf. The values are the expression mean of 6 wt and 4 neurod1^ΔUCE replicates. Genes underlined in grey are not significantly regulated (FDR > 0.1). S3 Table provides the expression level of all differentially expressed genes (values for each sample, means, log2 FC and FDR).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.