Figure 5
- ID
- ZDB-FIG-220324-44
- Publication
- Saraswathy et al., 2022 - The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent convergent extension movements during zebrafish gastrulation
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- Figure 1
- Figure 1—figure supplement 1.
- Figure 1—figure supplement 2.
- Figure 1—figure supplement 3.
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- Figure 3
- Figure 3—figure supplement 1.
- Figure 3—figure supplement 2.
- Figure 3—figure supplement 3.
- Figure 3—figure supplement 4.
- Figure 3—figure supplement 5.
- Figure 4
- Figure 4—figure supplement 1.
- Figure 5
- Figure 5—figure supplement 1.
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(A) Analysis of the axis extension angle α in bud stage embryos reveals that a subliminal dose of wnt5b morpholino (MO wnt5b) that has no effect on Convergent Extension (CE) in WT significantly enhances the defects observed in animals injected with mib1 morpholino (MO mib1). (B,C) wnt5b morpholino injection impairs CE in mib1tfi91 WT siblings (B) and enhances CE defects in mib1tfi91 homozygous mutants (C). (A–C) Lateral views of bud stage embryos, anterior up, dorsal to the right. Scalebars 200 µm. Boxes represent mean values ± SD. See Figure 5—source data 1 for complete statistical information.
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| Fish: | |
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| Knockdown Reagents: | |
| Observed In: | |
| Stage: | Bud |