FIGURE

FIGURE 4

ID

ZDB-FIG-211111-14

Publication

Qiang et al., 2021 - Fibroblast Growth Factor 21 Augments Autophagy and Reduces Apoptosis in Damaged Liver to Improve Tissue Regeneration in Zebrafish

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FIGURE 4

Fibroblast growth factor 21 accelerates liver cell regeneration after injury. Samples were collected at 0, 24, and 48 hpa to assess the production of new cells in the damaged liver. PCNA assay performed to assess the level of the formation of new cells in the damaged liver. Liver cells (green fluorescent Denra-NTR), stromal cells (blue fluorescent DAPI), and PCNA positive cells (red fluorescent). DMSO group: without Mtz treatment, DMSO was applied. Mtz group: after Mtz treatment, grow naturally. Mtz+FGF21 group: after Mtz treatment, treated with FGF21 standard protein (n = 40 per group, repeat 3 times for each test). Scale bar = 100 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cq1Tg
Condition:	chemical treatment by environment: metronidazole
Observed In:	regenerating tissue hepatocyte proliferation
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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