Figure 2
- ID
- ZDB-FIG-210902-324
- Publication
- Noschka et al., 2021 - Gran1: A Granulysin-Derived Peptide with Potent Activity against Intracellular Mycobacterium tuberculosis
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Activity of Gran1 against extracellular mycobacteria: Extracellular mycobacteria (2 × 106) were incubated with increasing concentrations of Gran1 followed by incubation with 3H-Uracil for 18 h. The 3H-Uracil uptake was measured by scintillation counting. Antibacterial activity was determined for (A) slow-growing strains M. kansasii (n = 4), M. avium (n = 5), M. bovis BCG (n = 5) and (B) fast-growing strains M. fortuitum (n = 4), M. vaccae (n = 5), and M. smegmatis (n = 5). Data points show the mean antibacterial activity (%) ± SEM calculated from triplicates of each independent experiment. Dotted horizontal lines indicate background activity of diluent control. |