FIGURE

Fig. 7.

ID

ZDB-FIG-210708-45

Publication

Sidik et al., 2021 - Exposure to ethanol leads to midfacial hypoplasia in a zebrafish model of FASD via indirect interactions with the Shh pathway

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Fig. 7.

Ethanol disrupts the polarity of membrane protrusions in vangl2 mutants. a Confocal images of mesodermal cells expressing memGFP at 10 hpf. Ethanol treatment from 6–10 hpf. b–c Rose diagram of filopodial projections representing length and distribution around the cells, using b 24 bins, divided into 15^° angles or c 4 bins, divided into 90^° angles. Horizontal plane (0^°) represents the mediolateral axis; vertical plane (90^°) represents the anterior-posterior axis. d Quantification of the number of filopodia. n=6, for each group (p < 0.05; Tukey’s honest test). P values provided in Additional file 9: Table S2

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	vangl2^m209/m209
Condition:	chemical treatment by environment: ethanol
Observed In:	blastomere filopodium
Stage:	Bud

Phenotype Detail

Acknowledgments

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