FIGURE

Figure 6

ID

ZDB-FIG-210707-124

Publication

Alexandre-Moreno et al., 2021 - Null cyp1b1 Activity in Zebrafish Leads to Variable Craniofacial Defects Associated with Altered Expression of Extracellular Matrix and Lipid Metabolism Genes

Other Figures

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Figure 6

Ocular histology of adult (seven months) cyp1b1-KO zebrafish with Ph2 craniofacial alterations (F3). (A–J) Semithin (500 nm) tissue sections were stained with toluidine blue. The squares and rectangles indicate the areas of the images magnified in the indicated panels. No significant differences were observed between the eyes of wildtype and cyp1b1-KO zebrafish siblings. Scale bar in (A,F): 500 μm. Scale bar in (B–D,G–I): 100 μm. Scale bar in (E,J): 25 μm. RPE: retinal pigment epithelium; PR: photoreceptors; ONL: outer nuclear layer; OPL: outer plexiform layer; INL: inner nuclear layer; IPL: inner plexiform layer; GCL: ganglion cell layer; CE: ciliary epithelium; AL: annular ligament; CEP: corneal epithelium; CEN: corneal endothelium; S: stroma. The images are representative of the results observed in three fishes of each genotype. Three tissue sections per eye were analyzed.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cyp1b1^ucl3/ucl3 (AB)
Observed In:	cornea eye retina
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.