Fig. 7

kapd is associated with genetic networks controlling the development of mDA neurons in zebrafish system. The diagram summarizes the sequential stages and the molecules involved in the mDA neuron embryonic development. The expression of kapd is involved in cranial neural crest induction and midbrain neural tube morphogenesis, which are prerequisites for differentiation and maturation of the mDA neurons at various embryonic stages. Lines depict possible interactions among these molecules and arrows indicate stimulatory effects. The green colored, delimited by a green box, molecules involved in mDA progenitors. The light blue colored groups in box and circle are involved in immature mDA neurons. The red colored area clusters the genes involved in mature mDA identity.