FIGURE

FIGURE 1

ID

ZDB-FIG-200829-52

Publication

Liu et al., 2020 - Genetic Deletion of miR-430 Disrupts Maternal-Zygotic Transition and Embryonic Body Plan

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FIGURE 1

Targeted deletion of miR-430 in zebrafish. (A) Genetic deletion of zebrafish miR-430 cluster using TALENs. A 79.8 kb genomic fragment containing the zebrafish miR-430 was deleted using two pairs of TALENs. The TALEN binding sites were shown in colors and the inserted nucleotides were shown in lower case letters. MiR-430 isoforms were indicated by colored short lines. (B)In situ hybridization detection of pri-mir-430 expression in the WT and miR-430^–/– mutant embryos at 4 hpf. (C) Expression profiles of mature miR-430 isoforms in the WT and miR-430^–/– mutant embryos (12 hpf) by small RNA deep sequencing. The numbers of normalized reads were indicated. TPM, transcripts per kilobase million.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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