FIGURE

Fig. S4

ID

ZDB-FIG-200727-19

Publication

Sinagoga et al., 2020 - Mitf-family transcription factor function is required within cranial neural crest cells to promote choroid fissure closure

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Fig. S4

Transplantation of wild-type cells does not affect eye development. A)Wild-type cells transplanted into the region of cNCC origin in a mitfa -/-;tfec +/- embryo shows no effect on eye development. B) Similarly, transplanted wild-types cells targeting the retina/RPE in mitfa -/-;tfec +/+ embryos show no effect on eye development. C) Serial sections of representative retina/RPE and cNCC transplanted embryos. CF closure phenotypes are only detected in retina/RPE cell transplanted embryos. Dorsal is up in all images. Scale bar = 100μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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