FIGURE

Fig 3

ID

ZDB-FIG-200702-26

Publication

Blanco-Sánchez et al., 2020 - yippee like 3 (ypel3) is a novel gene required for myelinating and perineurial glia development

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Fig 3

Specification and development of motoneurons are unaffected in maternal-zygotic <italic>ypel3</italic> mutants.

(A-F) Analysis of the pMN domain and its derivatives. Transverse sections. (A-C) WT. (D-F) maternal zygotic (mz) ypel3^-/-. (A, D) pMN domain and its derivatives labeled by olig2:kaede transgene. (B, E) Topro nuclear labeling. (C, F) Merge. (G-J) Analysis of motoneuron development in mz ypel3 mutants. Lateral views. Motoneurons are labeled by the mnx1:gfp transgene. (G-H) WT embryo at 26 hpf (G) and larva at 52 hpf (H). (I-J) mz ypel3 mutant at 26 hpf (I) and larva at 52 hpf (J). Images were taken at the level of somites 6 to10. (K-L) Quantification of the number of motoneurons at 26 hpf (K) and at 52 hpf (L). Bars show +/- SEM. Scale bars: 5 μm in A-F, 25 μm in G-J.

Expression Data

Genes:	GFP Kaede
Fish:	ypel3^b1310/b1310; ml2Tg ypel3^b1310/b1310; vu85Tg
Anatomical Term:	primary motor neuron
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ypel3^b1310/b1310; ml2Tg ypel3^b1310/b1310; vu85Tg
Observed In:	primary motor neuron
Stage Range:	Prim-5 to Long-pec

Phenotype Detail

Acknowledgments

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