FIGURE

Fig. 2

ID
ZDB-FIG-200325-49
Publication
Ren et al., 2020 - Igf2bp3 maintains maternal RNA stability and ensures early embryo development in zebrafish
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Fig. 2

M<italic>igf2bp3</italic> embryos exhibit abnormal cytoskeleton organization.

a, b Expression and distribution of F-actin and β-catenin in wild type and Migf2bp3 embryos at 2-, 4-, and 8-cell stages. The F-actin and β-catenin were enriched in mature and apparent cleavage furrow (triangle). The inset showed a zoom-in of the boxed region at each stage. Zoomed-out scale bar = 100 μm; zoomed-in scale bar = 50 μm. a Migf2bp3 embryos at 4-cell stage did neither exhibit intact adhesion junction of F-actin cables nor form the mature furrow (white arrow). b Migf2bp3 embryos exhibited reduced expression of β-catenin (white arrows) and did not form intact cell adhesion junction with defective furrow (white bracket). c Double localization of F-actin (green fluorescence) and CG (red fluorescence). The inset showed a zoom-in of the boxed region at each stage. Zoomed-out scale bar = 100 μm; zoomed-in scale bar = 50 μm.

Expression Data
Antibodies:
Fish:
Anatomical Term:
Stage: 4-cell

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: 2-cell

Phenotype Detail
Acknowledgments
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