FIGURE

Figure 1

ID

ZDB-FIG-200302-26

Publication

FitzSimons et al., 2020 - Cardiac injury modulates critical components of prostaglandin E₂ signaling during zebrafish heart regeneration

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Figure 1

Cardiac injury triggers an elevation in PGE₂ synthesis. (A,B) LC-MS/MS profiling showed that PGE₂ concentrations were significantly elevated above all other prostaglandin species analyzed in both the uninjured heart (A), and at 3 dpa (B). (mean ± s.e.m. n = 5 biological replicates; 5 pooled ventricles per replicate. One-way ANOVA followed by Tukey’s multiple comparisons test. ***P < 0.001). (C) LC-MS/MS analysis showed that PGE₂ concentrations were significantly higher at 3 dpa, relative to uninjured hearts. (mean ± s.e.m. n = 5 biological replicates; 5 pooled ventricles per replicate. Student’s t-test. *P < 0.05).

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Antibody Labeling

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