FIGURE

Figure EV5

ID

ZDB-FIG-200212-43

Publication

Ki et al., 2019 - CEP41-mediated ciliary tubulin glutamylation drives angiogenesis through AURKA-dependent deciliation

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Figure EV5

Enhanced angiogenesis by hypoxia induction is inhibited by <styled-content toggle='no' style='fixed-case'>CEP</styled-content>41 depletion in <styled-content toggle='no' style='fixed-case'>HUVEC</styled-content>s

An in vitro angiogenesis assay was performed in normoxia‐ or hypoxia‐exposed HUVECs transfected with control or CEP41 siRNAs for 18 h. Scale bars, 600 μm.

B, C

Quantification of tube node number in (B) and tube length in (C) from data examined within equivalent fields of view at each time point using the ImageJ angiogenesis analyzer. Data are shown as mean ± SD of five independent experiments with ≥ 5 tubulogenesis regions per condition. Statistical significance was determined using the two‐way ANOVA followed by Tukey's post hoc test (***P < 0.001, ns: non‐significant).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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