FIGURE

Fig. 5

ID

ZDB-FIG-191220-28

Publication

Xiao et al., 2019 - Novel truncation mutations in MYRF cause autosomal dominant high hyperopia mapped to 11p12-q13.3

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Fig. 5

Immunostaining images of labels for different retinal cells in zebrafish at 5 dpf. Frozen sections from wild-type larvae (a–a″, c–c″, and e–e″) and myrf MO-injected larvae (b–b″, d–d″, and f–f″). Zebrafish larvae were labeled with Hu C/D (ganglion cell and amacrine cell marker, green, a′ and b′), Pax 6 (ganglion and amacrine precursor cell marker, red, a′′ and b′′), Gs (Müller cell marker, green, c′ and d′), PKCα (bipolar cell marker, red, c′′ and d′′), Rho 1D4 (long double cone outer segment marker, green, e′ and f′), recoverin (cone bipolar cell marker, red, e″ and f″), and DAPI (nuclei, blue). No differences were detected in retinal development between wild-type larvae and myrf morphants. Scale bars represent 100 μm

Expression Data

Antibodies:	Ab1-elavl Ab1-glul Ab1-pax6 Ab1-prkca Ab2-recoverin Ab3-rho
Fish:	AB AB + MO1-myrf
Knockdown Reagent:	MO1-myrf
Anatomical Terms:	amacrine cell cone retinal bipolar cell Muller cell retinal bipolar neuron retinal cone cell cone photoreceptor outer segment retinal ganglion cell
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-myrf
Knockdown Reagent:	MO1-myrf
Observed In:	amacrine cell differentiation eye retina layer formation retinal bipolar neuron differentiation
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Hum. Genet.