FIGURE

Fig. 3

ID

ZDB-FIG-190823-20

Publication

Whitesell et al., 2019 - foxc1 is required for embryonic head vascular smooth muscle differentiation in zebrafish

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Fig. 3

foxc1b expressing perivascular cells in the embryonic ventral head co-express acta2. A) In ventral head vessels at 4 dpf, foxc1b:EGFP expressing cells are associated with, and surround, the endothelium (kdrl:mCherry) along the ventral aorta. B) Similarly, acta2:EGFP positive smooth muscle cells surround the kdrl:mCherrypositive endothelium along the ventral aorta and aortic arch arteries. C) foxc1b:EGFP and acta2:mCherry are co-expressed along the ventral aorta. Schematics depict mural cell and endothelial marker expression matching the transgenes. Grey indicates presumptive endothelial patterns. Arrowheads represent marker-expressing mural cells. Arrows show co-expression of two smooth muscle cell markers. Scale bars represent 50 μm.

Expression Data

Genes:	EGFP mCherry
Fish:	ca7Tg; ci5Tg ca8Tg; mw44Tg ci5Tg; mw44Tg
Anatomical Terms:	aortic arch blood vessel endothelium aortic arch vascular associated smooth muscle cell head blood vessel endothelium head vascular associated smooth muscle cell ventral aorta blood vessel endothelium ventral aorta vascular associated smooth muscle cell
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 453(1), Whitesell, T.R., Chrystal, P.W., Ryu, J.R., Munsie, N., Grosse, A., French, C.R., Workentine, M.L., Li, R., Zhu, L.J., Waskiewicz, A., Lehmann, O.J., Lawson, N.D., Childs, S.J., foxc1 is required for embryonic head vascular smooth muscle differentiation in zebrafish, 34-47, Copyright (2019) with permission from Elsevier. Full text @ Dev. Biol.