FIGURE

Fig. S2

ID

ZDB-FIG-190731-2

Publication

Gjini et al., 2019 - Disruption of asxl1 results in myeloproliferative neoplasms in zebrafish

Other Figures

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Fig. S2

Histopathological analysis of kidney, intestine and liver development in 17-month-old asxl1+/+ and asxl1+/- and asxl1-/- fish. Results revealed that intestine (D, E and F) and liver (G, H and I) was normal and similar to that of the fish, indicating that these fish recovered from early developmental hypoplasia in these organs. However, asxl1-/- mutants did have decreased numbers of erythroid islands in the kidney marrow compared with asxl1+/+ and asxl1+/- fish (A, B and C), indicating that the hematopoietic system is abnormal in these animals. Area encircled with black line indicates erythroid islands. The quantification of erythroid islands was shown in (J), with the black bars representing the median values. ns p>0.05, *p<0.05, **p<0.01 by two-tailed unpaired t-test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	asxl1^zdf34/zdf34
Observed In:	head kidney erythroid lineage cell hematopoietic system intestine liver
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.