FIGURE

Figure 2

ID

ZDB-FIG-190723-268

Publication

Richardson et al., 2011 - A zebrafish model for nevus regeneration

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Figure 2

Regenerating fish-nevi develop from an undifferentiated precursor. (A) A zebrafish tail fin with a fish-nevus (asterisks) was partially amputated and regrown in the presence of phenylthiourea (PTU) for 11 days (B). PTU blocks new melanin synthesis (Rawls and Johnson, 2000). Red boxes indicate areas of normal (top) and fish-nevus (bottom) regenerating fin. In the normal and fish-nevus (C and E), the fin regenerates in PTU without pigmentation and the blood vessels are clearly visible. (D and F) After 24 h in fresh water (PTU washout), the melanocytes are clearly visible (red arrows).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Pigment Cell Melanoma Res.